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Author information: In many egg-laying reptiles, the incubation temperature of the egg determines the sex of the offspring, a process known as temperature-dependent sex determination TSD.

In TSD sex determination is an "all or none" process and intersexes are rarely formed.

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How is the external signal of temperature transduced into a genetic signal that determines gonadal sex and channels sexual development? Studies with the red-eared slider turtle have focused on the physiological, biochemical, and molecular cascades initiated by the temperature signal.

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It indianudgirlsclub that temperature accomplishes this end by acting on genes encoding for steroidogenic enzymes and steroid hormone receptors and modifying the endocrine microenvironment in the embryo. The temperature experienced in development also has long-term functional outcomes in addition to sex determination.

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Research with the leopard gecko indicates that incubation temperature as well as steroid hormones serve as organizers in shaping the adult phenotype, with sex modulating sex hormone action in sexual differentiation.

Finally, practical applications of this research have emerged for the conservation and restoration of endangered egg-laying reptiles as well as the ultimate development of reptiles as biomarkers to monitor the estrogenic effects of common environmental contaminants.

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